Antibacterial Activity of Bay Leaf (Syzygium polyanthum) Ethanol Extract on Escherichia coli Growth
Abstract
Acute diarrhea is liquid stool with a frequency of more than 3 times a day and lasts less than 14 days. One of the most common causes of acute diarrhea is Escherichia coli. Diarrhea caused by bacteria can be treated with the use of antibiotics, but the relatively high intensity of antibiotic use causes various health problems, especially bacterial resistance. Therefore, the search for antibacterial agents derived from natural ingredients was carried out as an alternative treatment. Bay leaf (Syzygium polyanthum) is one of the natural ingredients that has the potential as an antibacterial because it contains active compounds such as essential oils, flavonoids (quercetin), saponins, tannins, and alkaloids. This study aimed to analyze the antibacterial activity of the ethanolic extract of bay leaves on the growth of Escherichia coli. This research uses the dilution method which aims to determine the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC). The results showed that the MIC value at a concentration of 200mg/ml and the MBC value at a concentration of 500mg/ml.
Downloads
References
Adrianto, A. W. D. (2012). Uji Daya Antibakteri Ekstrak Daun Salam (Eugenia polyantha Wight) dalam Pasta Gigi Terhadap Pertumbuhan Streptococcus mutans. Universitas Jember.
Algabri, S. O., Doro, B. M., Abadi, A. M., Shiba, M. A., & Salem, A. H. (2018). Bay Leaves have Antimicrobial and Antioxidant Activities. Journal of Pathogen Research, 1(1:3).
Depkes RI. (2011). Peraturan Menteri Kesehatan Republik Indonesia Tentang Pedoman Umum Penggunaan Antibiotik. Kementerian Kesehatan.
Dewanti, S., & Wahyudi, M. T. (2013). Antibacteri activity of bay leaf infuse (Folia Syzygium polyanthum wight) to Escherichia coli in-vitro. Jurnal Medika Planta, 1(4).
Evendi, A. (2017). Uji Fitokimia dan Anti Bakteri Ekstrak Daun Salam (Syzygium polyanthum) Terhadap Bakteri Salmonella typhi dan Escherichia coli Secara In Vitro. Mahakam Medical Laboratory Technology Journal, II(1), 2.
Hakim, R. F., Fakhrurrazi, & Ferisa, W. (2016). Pengaruh air rebusan daun salam (Eugenia polyantha wight) terhadap pertumbuhan Enterococcus faecalis. Journal of Syiah Kuala Dentistry Society, 1(1), 21–28.
Nasution, F. P. (2014). Penentuan Konsentrasi Hambat Minimal dan Konsentrasi Bunuh Minimal Ekstrak Etanol Daun Salam (Syxygium polyanthum) Terhadap Pertumbuhan Pseudomonas aeruginosa Isolat Klinis. ETD Unsyiah. Universitas Syiah Kuala.
Setiati, S., Alwi, I., Sudoyo, A. W., Simadibrata, M., Setiyohadi, B., & Syam, A. F. (2014). Buku Ajar Ilmu Penyakit Dalam. Interna Publishing (6th ed.). Jakarta.
Syahrurachman, A., Chatim, A., Soebandrio W.K., A., Karuniawati, A., Santoso, A. U. S., Harun, B. M. H., … dkk. (2019). Buku Ajar Mikrobiologi Kedokteran Edisi Revisi. Binarupa Aksara.
Utami, P. R. (2020). Uji daya hambat ekstrak daun salam (Syzygium polyanthum [Wight] Walp) terhadap pertumbuhan bakteri Escherichia coli. Jurnal Ilmiah Pannmed (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist), 15(2), 255–259.
Wilapangga, A., & Syaputra, S. (2018). Analisis Antibakteri metode Agar Cakram dan Uji Toksisitas menggunakan BSLT (Brine Shrimp Lethality Test) dari Ekstrak Metanol Daun Salam (Eugenia polyantha). Indonesian Journal of Biotechnology and Biodiversity, 2(2), 50–56.
World Health Organization. (2017). Diarrhoeal disease. Retrieved November 28, 2020, from https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease.
Copyright (c) 2022 Eliya Mursyida, Raissa Almira, Santi Widiasari, Olvaria Misfa
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Each article is copyrighted © by its author(s) and is published under license from the author(s).
When a paper is accepted for publication, authors will be requested to agree with the Creative Commons Attribution-Noncommercial-No Derivative Works 4.0
Abstract views: 458 , 
PDF downloads: 843
